Soliman's Lab Research Scope
Main Research Theme
The research scope of Soliman's Molecular Modeling and Drug Design Research Lab covers a wide range of computational and molecular modeling research areas with main focus on biological systems and drug design approaches, Protein-Protein Interactions, Protein folding and dynamics, nano-particle fabrications and nano-particle drug delivery systems
Project Categories
Applications Projects
Structure/pharmacophore-Drug Design Approaches
Proteins structures and dynamics using computational tools such as MD, PCA, RIN, ... etc
Understanding drug resistance mechanisms via different computational tools
QM/MM MD simulations
Quantitative Structure Activity Relationship (QSAR)
Conformational Analysis of biomolecules
Bioinformatics tools applications
Development Projects
New Docking Approach called "Loop Docking" to enhance docking results - developed in-house
Approaches to enhance binding free energy calculations results
Developing parameters for biomolecules: on-going projects
Software implementations: on-going projects
Experimental Projects:
Binding interactions using Microscale Thermophoresis (MST), including protein--protein interaction, drug binding affinities, polymer interactions etc.